// drug_interaction_checker
Enter a medication list — one drug per line, or paste a clinical note. The checker screens all pairs against a curated database of clinically significant interactions and grades them: contraindicated, major, or moderate.
// medication_list
Presets:
// Clinical decision support only. Always verify against current BNF / MIMS / institutional formulary before prescribing.
// results
// Enter a medication list and press Check to screen for interactions.
// The cardiology preset loads a typical high-risk polypharmacy case:
// warfarin + amiodarone + digoxin + furosemide + aspirin + simvastatin.
$ cat interaction_db.md
Curated database of ~90 clinically significant drug pairs, covering:
QTc prolongation, CYP2C9/3A4/1A2/2D6 interactions, serotonin syndrome,
triple whammy (ACEi + NSAID + diuretic → AKI), hyperkalaemia, opioid +
benzodiazepine respiratory depression, antifolate toxicity, and DOAC bleeding.
$ cat production_note.md
Production system integrates with RxNorm (NIH drug normalisation API) and
OpenFDA drug labelling for exhaustive pair coverage. Interactions are mapped
to FHIR R4 DetectedIssue resources and surfaced at prescribing time in the EHR.